Given that I live in the academic world, I have always been aware of the Holy Grails of publishing: Nature, Science, and maybe some other one-word wonders. I occasionally came across such papers in grad school, and I would read them, usually think they were pretty nice, and file them into the unorganized void in the back of my head.
- Anything published in a big journal is a god-send to Science.
- Anything published anywhere else is not worth reading.
It is the blind loyalty with which I take issue. For two reasons:
- Sometimes the revered journals publish crappy Science. For example, most of the articles published in PNAS are not subjected to (thorough) peer review because either the authors have a friend who is a member of the academy (Track 1) or one of the authors is a member of the academy (Track 3). Although most members are probably loathe to embarrass themselves by communicating garbage science to a prestigious journal organization, the fact of the matter is that plenty of crap gets through… enough to make me realize that coworker belief #1 is just not true.
- It goes without saying that there is plenty of quality science going on at non-Nature level. Fundamental studies that make significant headway in the understanding of basic scientific issues often wind up in trade journals. Sometimes, it is precisely this *understanding* that leads to Really Cool Application on the cover of Nature Biotech. We often overlook this key point.
I try not to get too worked up about the paper-reading preferences of my strange colleagues, but the longer I am here, the more I have to laugh. These people are really missing out.

